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Thereafter, the supernatant was transferred to a pre-chilled microfuge tube, left on ice in darkness for 15 min, and then passed through a 0.45 m PTFE filter

Mullally and coworkers found genomic islands (GIs) associated with hyperinvasive lineages (absent in cc53), which encode functions that facilitate meningococcal access to different cell types, leading to an increased risk for IMD (Mullally et al., 2021)