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For example, mutations in the IVD gene encoding the enzyme for leucine degradation cause isovaleric acidemia, in which the intermediate isovaleric acid accumulates and damages the brain and nervous system (Vockley and Ensenauer, 2006)

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Hyperhomocysteinemia and of Methylenetetrahydrofolate Reductase (C677T) Genetic Polymorphism in Patients with Deep Vein Thrombosis

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