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They cited studies that found that T4 doses that produced a low or suppressed TSH level and/or high FT4 levels were often associated with changes seen in hyperthyroidism, including increases in liver enzymes (26, 27), bone loss in women (28), and reduced cardiac systolic time intervals (29)

Two distinct mechanisms involved in the P

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In published endocrinology research, the two peptides act on distinct but complementary pathways: GHRH-receptor activation increases the amplitude of natural GH pulses, while a selective GH secretagogue can synergistically increase pulse frequency