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Animals received a single intravenous (IV) injection (0.2 mL) of Co-60 solution at 7.2 0.5 KBq dose in sterile saline via an indwelling jugular vein cannula

Disturbance of the lens cell membrane permeability during the development of cataract, and reduced ability of active transport of substances against the concentration gradient lead to changes in concentration of intracellular compounds and metabolic changes within the cells

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Stromal vascular fraction (SVF) cells were isolated from WAT of Ssu72 WT and aKO mice and sub-cultured in vitro

Protein aggregates then inhibit proteasomes, the main organelles in the cell for degradation of abnormal proteins (Chen et al., 2012