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172 Rodent 173 and human studies 174 reveal that leptin also modulates glucose and lipid metabolism through a brainvagusliver axis and hypothalamicpituitaryadrenal signaling, contributing to adverse communication among adipose tissue, the hypothalamus, the liver and the pancreas, exacerbating T2D

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Science 355 , 12061211 (2017)

Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch

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