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Gleason A, et al

Furthermore, IR increases hepatic De novo lipogenesis (DNL) and stimulates adipose tissue to secrete adipokine and inflammatory cytokine, ultimately leading to the dysregulation of adipose tissues lipolytic processes [26]

Specifically, 50% of the children had increased eye contact and attention to directions, 3050% of children showed improvement in retaining learned tasks, 10% of the children started speaking words and even sentences, and lower incidence of hyperactivity and aggression

This means that Nrf2 is responsible for detecting cellular damage