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Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells

Oxidative stress and cognitive decline: the neuroprotective role of natural antioxidants

Alcohol and Nicotine: Briefly Noted While not supplements, its worth noting two common substances: Alcohol: Alcohol can feel like it calms you initially (it increases GABA and dopamine short-term), but it also raises adrenaline and disrupts sleep, and the aldehydes from alcohol metabolism can burden detox pathways that overlap with COMTs work

Although modulating B-cell-driven inflammatory amplification may hold therapeutic value, current evidence is still insufficient to support B cells as a direct therapeutic target, especially given that most mechanistic data derive from murine models and their contribution to human disease remains uncertain

J., Walensky, L