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An extensive study in the United States found that pernicious anemia patients also had an increased risk of 10 different types of cancer

doi:10.1016/j.annemergmed.2013.06.022 Mayo Clinic

Absorption of vitamin B 12 is inhibited from both dietary sources and from the bile (enterohepatic circulation) and thus depletion of vitamin B 12 body stores can occur relatively quickly

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