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4 Other trials on NAD+ for addiction typically had patients use 500-1000mg of NAD+ in 300mL of normal saline typically with a loading period of daily dosing for four days, followed by a taper period of twice weekly dosing for a month, and finally reducing to just twice monthly dosing until resolution of addiction

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* Percent Daily Values are based on a 2,000 calorie diet

They usually cause no symptoms, except during rupture

Among the tested derivatives, a compound known as A4 showed the most promising results, surpassing other curcumin derivatives in efficacy (456)