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Description

It plays a role in the methylation process, which is crucial for various essential functions such as detoxification, neurotransmitter production, and gene regulation

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10.1016/j.ntt.2013.04.001 Neurotoxicol

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Requirements of a First in Human Clinical Trial A First in Human clinical trial must meet specific requirements, including: Data on the Quality of the Investigated Drug Thorough evaluation of the pharmaceutical formulations quality is essential before commencing the clinical trial

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In an ischemic mouse model, lactate was shown to trigger astrogliosis through the activation of Akt and STAT3 signaling pathways, further linking metabolic shifts to astrocyte reactivity 78

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