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Endothelial progenitor cells, endothelial dysfunction, inflammation, and oxidative stress in hypertension

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The first incorporates GSH into the mitochondria by inorganic phosphate exchange and the second by exchange of 2-oxoglutarate (27, 28, 64) (Figures 2, 4)

Excitingly, imaging mass spectrometry, in which a tissue slice is coated with matrix and then ionized by a laser pulse (MALDI), offers the prospect of visualizing them at single-cell resolution 180,181 , although proof of principle for PPP metabolites remains to be established