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Schmitt T, Oehme L, Andreeff M , Foe Owono GD, Franke WG, Freyer R

major genes to 926 FDA-approved drugs (see Additional file 2)

All experiments were approved by the ethical board of the Niederschsisches Landesamt fr Verbraucherschutz und Lebensmittelsicherheit, Oldenburg, or by the Bavarian government (Regierung von Oberbayern, permit number ROB-55.2-2532.Vet_02-23-90)

A previous study revealed that circulating hypoxic conditions increase ROS production, activate HIF-1, and promote the growth of glioma cells by upregulating the expression of NOX4 mRNA and protein expression in GBM cells ( A study identified that diacylglycerol O-acyltransferase 1 (DGAT1) is highly expressed in HGGs