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Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics

Mashimo T, Pichumani K, Vemireddy V, Hatanpaa KJ, Singh DK, Sirasanagandla S, et al

The binding of B12-IF complex to the cubam receptors triggers receptor intake where the whole B12-IF-cubam receptor complex is taken into the ileal cell

In fact, this work was based on previous data confirming the presence of IGF-I receptors in brain capillary endothelial cells (which constitute the BBB), and their role in internalizing IGFs to the CNS from the circulation[65, 66]