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[PubMed: 22330623] 414

p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance

The symptoms evolved over the course of one and a half days to a complete paraplegic syndrome including anesthesia below dermatome T6, absent tendon reflexes of the lower extremities and detrusor areflexia with urinary retention

doi: 10.1515/BC.2009.033 4 CavalcantiY

Higher-Caution Situations Extra medical supervision is important if you: have a history of reactions to injectable vitamins/cobalamins have significant kidney or liver disease are pregnant or breastfeeding are offered a compounded MIC B12 product without clear labeling of ingredients, concentrations, and compounding source The FDAs overview of compounding helps explain why quality can vary (see Compounding and the FDA: Questions and Answers )