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Bettencourt C, Foti SC, Miki Y, Botia J, Chatterjee A, Warner TT, Revesz T, Lashley T, Balazs R, Vir E, Holton JL (2020) White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy

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And then if they have posterior instability, Im probably going to be careful with range of motion across their body moving into horizontal abduction and probably internal rotation, as well early on probably it, depending on the severity of the instability, maybe avoid those positions early on and then gradually reintroduce that range of motion and strength and into that range of motion over time

Now you need to draw accurate doses from it every day (or however often your protocol requires)

As my own experience it would be good to report my experience