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Given this, based on the above antioxidant classification and defense categories, we selected antioxidants that are more studied in CIPN and have a more significant role in a systematic review to provide a reference for the future application and continued research of antioxidants in CIPN

The gene ribR encodes a monofunctional flavokinase as a part of the transcription unit consisting of 12 genes, whose products are involved in sulfur uptake and degradation

Alteration in homeostatic status leads to a shift in the dynamic equilibrium of metabolism toward the ROS generation thereby oxidative stress leading to organ malfunction

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Conditions such as congestive heart failure, edema, or hypertension can be exacerbated by the fluid retention cause by suboptimal renal perfusion