This suggests that there is a similar basis of their mechanism of action that is the allosteric modulation of GABA receptors
J Physiol 581 , 389403, doi:10.1113/jphysiol.2007.129700 (2007)

Product Attributes CAS # : 62568-57-4 Molecular Formula : C35H48N10O15 Sequence (AA) : WAGGDASGE Molecular Weight : 848.8 g/mol PubChem CID : 68816 Half-Life : ~7-15 minutes Synonyms : Delta Sleep-Inducing Peptide, DSIP-9, Delta-Sleep Inducing Nonapeptide Type : Endogenous research neuropeptide (nonapeptide) Research Focus : Sleep & Recovery, Stress & Neuroendocrine Modulation Scientific References Delta sleep-inducing peptide (DSIP): a review Observational | Animal | In vitro Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients Human RCT | Observational The delta sleep-inducing peptide (DSIP): a still unresolved riddle Animal | In vitro DSIP in the treatment of chronic insomnia: a double-blind clinical trial Human RCT Influence of DSIP on the secretion of pituitary hormones in humans Observational | Human RCT Delta sleep-inducing peptide modulates the stress response in rats Animal Delta sleep-inducing peptide: structure, function and clinical perspectives Observational | Animal | In vitro Antioxidant properties of delta sleep-inducing peptide in experimental models Animal | In vitro Included In The Box Every product arrives in a premium, custom-designed PEPTIDE.Power box , engineered for convenience, hygiene, and safe storage in your refrigerator

By dampening CRH output, this process may reduce the downstream cascade of ACTH and cortisol release that characterizes the stress response
Others benefit from a slower introduction