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Evidence from preclinical and clinical studies suggests that Cannabis sativa derived compounds may influence processes associated with depressive symptoms through mechanisms involving the endocannabinoid system and related molecular pathways

Plasma and red blood cell membrane accretion and pharmacokinetics of RT001 (bis-allylic 11,11-D2-linoleic acid ethyl ester) during long term dosing in patients

A high-fat high-fructose diet dysregulates the homeostatic crosstalk between gut microbiome, metabolome, and immunity in an experimental model of obesity

Additionally, the presence of immunosuppressive cells (e.g., regulatory T cells) in the tumor microenvironment (TME) and changes in the extracellular matrix are known to accelerate the progression of the disease (Xu et al., 2021)