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Imagine this scenario: you've carefully calculated a dose of 250mcg for your research subject

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they answer different research questions, and the choice is a design decision rather than a dosing one

That is, we finalized at 410.30 to include orally and enterally administered compounded formulations with active ingredients derived only from FDA-approved drugs that have approved immunosuppressive indications or FDA-approved drugs that have been determined by a MAC to be reasonable and necessary for a specific purpose in immunosuppressive treatment included in the immunosuppressive drug benefit

Proc Natl Acad Sci U S A , 110 (52), 2100621011