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Un sujeto (1.6%) reporto evacuaciones diarreicas las cuales no ameritaron terapia concomitante y un sujeto (1.6%) reporto estreimiento, requiriendo modificaciones dietticas con incremento de fibra y lquidos no fue necesario empleo de terapia farmacolgica (Tabla 13)

doi: 10.1179/1351000215Y.0000000040

Persistent activation of this pathway, potentially driven by chronic cellular stress, unresolved DNA damage, or microbial dysbiosis, can sustain a pro-inflammatory and pro-fibrotic renal microenvironment [37]

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Despite a plethora of primary physiological functions, several studies have shown an imbalance between arginase and NOS activity in oxidative stress conditions