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The cultures were then centrifuged at 6,000 rpm for 10 min at 4C, after which the bacterial pellets were washed twice with PBS

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However, further studies are necessary to determine whether NRDE2 deficiency could be used as a biomarker for PARP-1 inhibitor response in other cancer types or if the loss of other genes may have an impact comparable to that of NRDE2 (158)

The therapeutic effect of GDNF is time-dependent: early intervention during the reversible stage of neuronal degeneration yields significantly better outcomes than late intervention, highlighting its potential as a disease-modifying agent

Underlying mechanisms responsible for restriction of uptake and translocation of heavy metals (metalloids) by selenium via root application in plants