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IGF-1 LR3 is typically administered via subcutaneous or intramuscular injection

treated chicken myotubes with IGF-1 and found that LC3-I to LC3-II conversion, a critical step for autophagosome formation, was decreased [64]

References Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Wei M, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD: Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

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