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Your body naturally produces glutathione, but levels decrease with age, stress, and toxin exposure, which is why supplementation with glutathione may help

For instance, exposure to manganese can decrease the levels of GSH and the activity of antioxidant enzymes like CAT, GPx, SOD, and GST in rat models

Frontiers in Pharmacology , 13, 1026182

Consistent with its disruptions of mitochondrial respiration reflected in the cells OCR measurements, CB-839, starting at low concentrations of 0.1 to 1 M, also decreased the ATP pool in the HG-3 (P = 0.02) and MEC-1 (P = 0.01) cell lines, as measured using high-performance liquid chromatography ( Figure 2D ).The levels of other nucleotides remained stable at all concentration points

Yes, lemon water is rich in vitamin C, which helps the body recycle and maintain glutathione levels