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113 In addition, gain of function mutation of NLRP3 leads to a group of autoinflammatory disorders known as cryopyrin associated periodic syndromes (CAPS), including neonatal-onset multisystem inflammatory disease, and familial cold autoinflammatory syndrome and Muckle-Wells syndrome

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10.1038/nrm.2016.23 93 RoncoC.BellomoR.KellumJ