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Transport and subcellular distribution of intranasally administered zinc in the olfactory system of rats and pikes

If a lack of vitamin B12 prevents the brain from making these chemicals, you may experience common depressive symptoms, like: Anxiety Irritability Sadness Restlessness Additionally, a B12 deficiency can: Lead to increased amounts of the amino acid homocysteine, which can make depression worse [9]

Moreover, in some conditions there may be an ectopic production of thyroid hormones, leading to increased thyroid hormones and a compensatory decrease of TSH, Table 1 (Oo KM n.d