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November 12 Product: Intercept Pharmaceuticals Ocaliva Indication: Primary biliary cholangitis After initially delaying its decision last month, the FDA on Tuesday declined to give Intercept Pharmaceuticals Ocaliva (obeticholic acid) full approval for primary biliary cholangitis (PBC)

A role of HLA-I peptide complexes and the endoplasmic reticulum aminopeptidase (ERAP)1 in the regulation of MB cell killing has been reported (167)

Each stage requires a specific enzyme and a splash of energy in the form of ATP (adenosine triphosphate)

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