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APP showed a partial co-localisation with both RAB5A and RAB11A, consistent with its steady state localisation in both early and recycling endosomes (Fig

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revealed that the LN microenvironment can reprogram cancer cells, leading to an elevation in interferon-induced gene signatures, which subsequently caused the upregulation of MHC class I and PD-L1 gene expression in cancer cells (57)

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There are more cynical interpretations than that, but I think that says that theres a huge problem in psychiatry of not having confidence in their patients