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NOTE ADDED IN PROOF After this article was submitted for publication on January 2, 2013, the following article was published prior to publication which strongly supports the hypothesis in the current article

For statistical analysis presented as fold change (bar graphs), the mean of data from control samples was assigned a value of 1 and all other samples were calculated relative to the control

Free Radic Res 26: 209-234

The two conformations differ in the position of the polar sugar moiety and in the orientation of the indole that is 180 rotated with respect to each other (Fig