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doi: 10.1124/dmd.110.032813

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For Y2H assays, the plasmids of pGADT7 (empty vector) or pGADT7 derivatives were introduced into the yeast strain AH109 with plasmids of pGBKT7 (empty vector) or pGBKT7 derivatives

The following experimental evidence supports the hypothesis: (i) asparagine and serine concentrations in cancer cells are higher than in normal ones (Bi and Henry, Figure 6 Glutamine and ROS scavenging Besides energy production, glutamine is also involved in regulation of ROS scavenging that represents another cross road for cancer cells that are under ROS stress and enhanced glutathione (Glutamate-Glycine-Cysteine-GSH) synthesis (Newsholme et al., 2003

Systematic investigation of mouse models of Parkinsons disease by transcriptome mapping on a brain-specific genome-scale metabolic network