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Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity

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Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells

The study first constructed an emotional attachment evaluation index system for small-scale urban vitality space based on the emotional attachment theory from a multidisciplinary perspective, including 14 indicators describing the degree, dimension, and intensity of attachment to specific built environment characteristics

Both mechanisms directly address impaired blood flow in hemorrhoidal tissue