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Additionally adverse childhood experiences are associated with stronger functional connectivity within the medial prefrontal cortex (mPFC) and between mPFC and other frontal regions, which may relate to repetitive self-referential processing, such as rumination (100)

And finally, alcohol metabolism uses up a lot of your B vitamins, which are vital for energy and detoxification

If youre thinking about B12 supplements, talk to a doctor first

L., Isaak, C

Allegaert K, de Hoon J, Verbesselt R et al , Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates