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Hooda Z, Werner R, Ries S, Eisenberg M, Hofstetter W, Mehran R, Rajaram R, Rice D, Swisher S, Vaporciyan A, Walsh G, Opitz I, Mitchell K, Antonoff M

Additionally, taurine assists in detoxification by conjugating bile acids, which helps eliminate metabolic waste products and reduces oxidative stress [88]

Therefore, these data suggest that the capacity of MAT2A inhibition via PF-9366 may be dependent on MAT2B levels or methionine/ATP availability

A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer