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Alternatively, in CD8 + T cells, excess glutarate has pleotropic effects on metabolism, altering Lp glu , K glu and also competitively inhibiting 2-OGDDs 9

Cellular senescence and senolytics: the path to the clinic | Nature Medicine n.d

Treated mice maintained normal blood glucose and insulin levels despite a fat-rich diet, indicating MOTS-cs potential to protect against obesity and metabolic syndrome