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Diabetes & metabolism journal

Kuhnthione Inj

The first clinical trial, titled A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of BG00012 in Combination with Methotrexate in Patients with Active RA Who Have Inadequate Response to Conventional Disease-Modifying Anti-Rheumatic Drug Therapy (NCT00810836, 20012010), was initiated by Biogen and involved 153 participants

By generating and utilizing mutants of ATG2A, wherein the predicted cysteines were substituted with serine, we observed a significant reduction in the S-palmitoylation level following the alteration of conserved C-terminal C1704, C1713, and C1714 (Fig