sbir dsip DoD 25.1 and STTR 25.A Solicitations Open Soon DoD | SBIR

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Figure 2: Time spent in the target quadrant by test subjects in each experimental treatment group

Cold therapy within the first 24-48 hours constricts blood vessels to limit bruise spread, while heat application afterward (day 3+) promotes healing and blood reabsorption

BPC-157 upregulates survival genes (Akt1, KRAS, Src, Foxo1), reduces inflammatory mediators (IL-6, TNF-, NOS2, NFB), scavenges reactive oxygen species through its four carboxylic groups, activates vascular bypass pathways, and maintains blood flow despite vessel occlusion

These reactions are typically self-limiting and resolve within 24 to 48 hours