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However, although lipids can be stored in lipid droplets to maintain lipid homeostasis, lipid accumulation can become pathogenic

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Indeed, in AD models, the effects of mitochondrial ROS were found to be much smaller compared with those of NOX-produced ROS (Angelova and Abramov, 2018)

2.15 Real-time quantitative PCR Total RNA was extracted from aortic tissue and endothelial cells using TRIzol reagent (Takara Bio Inc., 9108), following the manufacturers instructions