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Two of the transgenic lines, GSH2-lin-3XFLAG #7C and GSH2-lin-3XFLAG #7D, were chosen for immunolocalization study because they had relatively high GSH2-3xFLAG protein level

The physiologic significance of the hormone effect was confirmed using in vivo models such as insulin-deficient diabetic or adrenalectomized rats

Extensive evidence suggests that the proven therapeutic properties of N-acetylcysteine, through increasing endogenous antioxidants such as glutathione to prevent oxidative stress and reduce inflammation, are essential for improving liver function in patients undergoing liver surgery 21

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2022;8(37):eabm9427.[DOI] 51