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Here's the TL;DR on vitamin timing: while there is no official medical advice dictating that you should take vitamin supplements at a specific time of day to improve their efficiency, there is quite a lot of research showing that avoiding some vitamin supplements at particular times (or more accurately, with particular meals) can improve absorption, or that taking some vitamins alongside food can reduce the risk of adverse side effects

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The body absorbs B12 through a complex mechanism involving intrinsic factor, a protein produced in the stomach

Finally, a doctor tested for Intrinsic Factor Anti-body, which prevents B12 absorption

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