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Interestingly, the purified COP1-c-Jun complex also yielded detectable c-Jun ubiquitination, although to a lesser extent than reactions containing the full CRL4 DET1-COP1 complex with Ube2d3 (Fig

Hepatology 75 , 2842 (2022)

Among patients receiving checkpoint inhibitors, the most commonly affected parts of the body are the skin, colon, endocrine system, liver, lungs, heart, musculoskeletal system, and central nervous system, Drs