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Hence, the maximum possible value of the programs causal effect, which uses all the information generated from this experiment, is the smaller of +0.28 and +0.8, so +0.28

In the presence of senescence cells and the sterile inflammation, the levels of the ectoenzyme CD38 appear to increase in immune cells and tissues, degrading extracellular NMN to NAM, and causing a decrease in NMN/NAD + levels in tissues (2)