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Pharmacokinetic studies reveal S-Acetyl-L-glutathione's rapid metabolism to GSH post-administration, enhancing bioavailability and indicating a more effective method to elevate GSH levels compared to direct supplementation

Larger studies are needed to validate these results and explore underlying mechanisms

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As an epigenetic modulator, succinate also suppresses histone and DNA methylation, supporting prolonged expression of glycolysis-related genes (181)