are vitamin b12 injections intramuscular at Home - Safety Guide for Self-Administration Best Vitamin B12 Injection Site:

In fact, vitamin B12 deficiency is a known contributor to neural tube defects

By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways

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Without enough platelets in the blood, the patient may experience mild or more severe uncontrolled bleeding, both externally and internally

This is especially true for those with dietary restrictions