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Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Glutathione mitigates hypoxia stress induced liver injury in juvenile grass carp (Ctenopharyngodon idellus) by alleviating mitochondrial dysfunction and autophagy ScienceDirect Functions of glutathione degrading enzymes in tumors. The functions of Download Scientific Diagram Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Cell Death & Disease Understanding the Autophagy Pathway: A Critical Process in Cellular Maintenance Assay Genie
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