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While the functional unit is a homotrimer in membranes, the dominant catalytically active organization of soluble GSTs is a dimer

537 Lipid peroxidation associated with ferroptosis accelerates the development of atherosclerosis

[78] N-acetylcysteine may also destabilize the disulfide bonds in clotting factors and modestly prolong the International Normalized Ratio, though this may not be clinically significant

10.1093/ijnp/pyaa060 201 SaijoK.WinnerB.CarsonC

However, its efficacy varies between patients and with different classes of chemotherapy, and a large proportion of patients may still lose up to 50% of their hair