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The current body of research has reached a consensus that DUX4 is the primary therapeutic target for FSHD (813)

Hyaluronic acid: Among the best-loved hydrators, hyaluronic acid is an ideal match for tretinoin

CEBPB, activated of Akt, binds the COL11A1 promoter to stabilize PDK1 and recruits DOT1L to mediate H3K79 methylation at resistance loci, maintaining an open chromatin configuration [109, 110] (Fig