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Additionally, our in vitro model lacks the complex multicellular and immune environment as well as mechanical forces in the lung, which play a crucial role in lung fibrogenesis and fibrosis progression

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2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury

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The metabolites and the pathways to which they belong have been grouped into five groups viz.-(i) Central Carbon metabolism (glce, glcc, g6p, f6p, f16bp, gap, dhap, 1,3bpg, 3pg, akg), (ii) Amino Acid metabolism (3php, pser, ser, gly, cyse, cys, cysL, glute, glut), (iii) Thiol metabolism (glucys, gsh, gssg), (iv) h2o2 production and metabolism (O2(ex), O2, oxrad, h2o2) (v) Redox metabolism (nadph, nadp+)