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For those with a high out-of-pocket burden, we discuss dosing frequency adjustments to balance budget with effectiveness

Comment: One commenter noted the Medicare Payment Advisory Commission's (MedPAC) 2016 Report to the Congress, in which MedPAC recommended that CMS reduce Part B drug supply fees to match those of other payers, as Medicare supply fees have been found to be substantially higher than those paid by other payers

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