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Zhou Z, Niu H, Bian M, Zhu C

The mononuclear phagocyte system

This method comprises administering to the subject an effective amount of a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound having the structure of formula (IV): Suitable and preferred compounds including preferred R 1 groups, compounds of formula (V), and SRS13-10F2, are as set forth above

Critically, ACSS2 inhibition reverses PD-L1 upregulation and rescues CD8 + T cell function in murine and human NSCLC models (229)

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