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Skin and dermal rejuvenation: In vitro and in vivo skin models where Epithalon enhances fibroblast activation, reduces apoptosis, and promotes normalized extracellular matrix production (e.g., collagen and elastin), supporting more youthful dermal architecture

Diet and lifestyle may also cause cellulite as a high fat and carbs will cause excess fat in the skin

Excess glucocorticoid exposure suppresses GH secretion mainly through the increase in hypothalamic somatostatin tone, whereas low cortisol levels causes relative GHD that is reversible by glucocorticoid therapy (Giustinas effect) ( Figure 5 ) (104)

Inflammatory pathways of importance for management of inflammatory bowel disease

It supports DNA repair, improved sleep patterns, and balanced circadian rhythm