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Subsequent research work in human subjects may be required to collect additional data on safety, tolerability, pharmacokinetic properties and efficacy in the target group of patients before a compound or drug can be implemented clinically [265, 266]

Tini P, et al

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To date, more than 18 million individuals worldwide have been diagnosed with RA, making it one of the most prevalent autoimmune diseases globally and posing a significant threat to public health and safety

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